3-Fluorophenmetrazine (3-FPM)


3-Fluorophenmetrazine is a novel stimulant based on phenmetrazine. It has been sold publicly since October 2014.

3-Fluorophenmetrazine (3-FPM)

Structure of 3-FPM.


Despite being a popular abusable prescription drug until the mid 1970s phenmetrazine (referred to as PM herein) has never been sold publicly on modern black markets and as a result no reports have ever been submitted to Erowid. Perhaps more surprising given the fast-moving nature of the novel substance market is that no other analogues of phenmetrazine have been seen and 3-FPM was not publicly sold until October 2014.

From what information can be gathered about the parent compound it appears that the addition of fluorine has minimally changed the original compound. 3-FPM appears to be a similarly functional stimulant with a similar dosage range.

The duration does appear to be increased slightly and there is suggestion that protracted (“binge”) dosing can keep sleep at bay for considerably longer than would otherwise be expected. This is not surprising given that a possible metabolite would be 3F-ephedrine and the resistance to metabolism conferred by fluorine would cause both this and 3-FPM to hang around longer. In addition to this, and not unusually for a functional stimulant, there appears to be a “ceiling effect” whereby after a certain level the desirable effects are not significantly increased by taking more, but the desire to redose and negative side effects are strengthened.

Given that phenmetrazine is a releasing agent and 3-FPM is so closely related it is very reasonable to assume that its action is exerted as a dopamine/norepinephrine releasing agent (NDRA).

Of course, the modification to the structure does allow 3-FPM to evade legislation and it is currently not specifically scheduled in most countries, meaning it is essentially legal to possess in many jurisdictions.

From a single low dose the headspace is quite clear with little feeling of being “high”, though the physical side effects are easily noticeable at medium doses and above.

Dose: 30-60 mg (oral) (insufflation is extremely painful)

Duration: 5-7 Hours (oral, single dose)


14:16 – 36mg orally
14:39 – I do feel slightly sped up.
15:10 – pretty mild though
15:19 – certainly a pleasant mood lift
16:21 – A subtle but pleasant headspace change exists. Equivalent to perhaps 20mg of 2-FMA
16:45 – Managing a website, I am easily staying focused. Sweating a bit more than normal
17:33 – losing focus more easily now
19:09 – I go to the pub and am marginally more chatty
21:19 – I eat a well sized meal, my appetite doesn’t seem diminished.

Several months later:

15:43 – 36.0 mg oral, light stomach contents
16:37 – Slightly sped up, nothing serious. Nice headspace and slight moodlift. Slight increase in sweating.
17:06 – Feeling reasonably chatty, slightly uplifted
18:13 – The effects are still very mild and not very noticeable but the lethargy I did have is totally gone and I have been productively editing, organising and doing chores. I didn’t get much increased sweatiness this time but have been drinking and urinating more.
19:00 – Still a pleasant noticeable buzz
20:30 – I eat dinner without much issue
22:34 – Not feeling anything now

Conclusion: A fairly average stimulant without many notable features. The unwelcome sleeplessness and diminishing returns at high doses have (happily) limited the popularity of 3-FPM somewhat but it is a viable stimulant for use as a study aid or general productivity enhancer in low doses.

HDMP-28 / Methylnaphthidate


HDMP-28 is a methylphenidate (ritalin, concerta) analogue which replaces the phenyl moiety with a naphthyl moiety.

Methylphenidate and HDMP-28

Methylphenidate and Methylnaphthidate


The modification confers a theoretical increase in SERT affinity, making effects closer to cocaine, and also theoretically gives increased potency over methylphenidate.

Despite being known about in scientific literature for many years, HDMP-28 is unusual in that it did not come to market until 2014. This is in stark contrast to many other known recreational drug analogues which were primarily surrected from the literature between 2010-2013.

The naphthyl moiety has caused some concern with comparisons drawn to naphthalene, but in the same way that we do not compare phenethylamines to benzene these concerns are not valid. The similar duration to methylphenidate offers additional reassurance, suggesting that the primary metabolic route is to the (naphthyl)ritalinic acid; which will be readily excreted.

Reports are still relatively scarce at this point and I struggled to find any which did not involve other drugs or multiple doses.

Dose: 30-60 mg

Duration: 5-7 Hours, Oral


10:14 – HR 67 bpm
10:15 – 34.8mg placed in mouth with water. There is an obvious taste of naphthalene but I press on because the “characteristic odor is detectable at concentrations as low as 0.08 ppm by mass”. Other than this it is not the most bitter of compounds.
10:40 – Maybe I am more focused and maybe there is a mood lift but it is mild and could be placebo
10:44 – Some tingles and definitely a mood lift so it wasn’t placebo
10:56 – Nothing more than that though
11:21 – Noticeably increased focus, a good functional level
11:43 – I am pretty engrossed in playing with my vape making some ejuices
12:03 – My girlfriend comes home. I am still feeling quite productive and chat to her while fixing a mirror
12:53 – I manage to eat a serving of protein shake/oats without issue despite not being hungry
13:25 – We have great sex and I have no problems maintaining an erection though do last longer than normal
14:00 – I feel very serene lying in bed with her
14:16 – We chat for a bit longer and she leaves to visit her mother. I still feel nicely stimulated, perhaps more noticeably than when she arrived.
14:35 – HR ~80bpm
14:43 – Not sure if I’m higher or just starting to feel a bit uncomfortable from coming down
15:11 – Certainly more noticeable headspace than earlier. Still not sure if it’s an enjoyable one.
15:22 – Not very good at deciding if I’m hot or cold
15:52 – Intensity of sensations have lessened
16:24 – Certainly on the way down now
17:19 – Have been thoroughly engrossed in design work for a new project, probably sober now. No comedown noticeable.

Conclusion: At this dose it is a mild stimulant but there is no hint of the promises made by the available pharmacological data. It certainly appears less potent than methylphenidate, a good 66% less. Additionally the serotonergic affinity seems unchanged at best, with no signs of real recreational potential. Certainly the lack of comedown warrants experimentation at higher doses, and the increased duration makes it miles better than ethylphenidate, but I won’t be expecting greatness from this one.



LSD is a classic and well known psychedelic drug known to be well tolerated physiologically by almost all users. Until recently very few analogues existed due to the relative difficulty of synthesising the lysergic acid backbone but in recent years constant scheduling of lower-hanging fruit has forced innovation in the novel psychoactive substance industry and a number of lysergamides have emerged as a result.

1-Acetyl-LSD (ALD-52) is somewhat notorious for its sale as “Orange Sunshine Acid” in California in the 1960s but has remained mysterious due to the theory that it might degrade to LSD combined with the slightly increased synthetic complexity putting off would-be chemists.

Despite being used to convict the manufacturers, the scientific principle behind this theory is incredibly unstable, with the acetyl group being used in laboratories around the world as a protecting group for indoles like LSD. Once attached, the group is resistant to removal except in extremely acidic or basic pH.

As a result of this rarity ALD-52 has never been confirmed as being sold and its activity has remained shrouded in mystery in recent times, with most assuming it to act as a pro-drug for LSD.

Despite this uncertainty and lack of sales the propionyl homologue has recently appeared on the market. This compound has not been reported on in any literature and is entirely unknown but given its similarity to LSD and ALD-52 the SAR reliably suggests an extremely similar effect profile.



Qualitative discussion:

Despite the prevailing theory about 1P-LSD, it appears not to be an LSD pro-drug. It has both a shorter duration and an extremely close potency, two things which are rarely associated with a pro-drug, especially in combination.

The dose appeared to come on slightly slower than that of LSD but quickly built to full intensity following this. The subjective effects were very similar to those of LSD, perhaps with a slightly more disorientating come-up. The differences become evident around the five hour mark, where a distinct lessening of effects is evident. From here there is a gentle descent to sobriety over approximately 3-4 hours, giving a total duration of approximately 8-10 hours.

Pleasingly there appears to be little incidence of “body load”, unlike that seen with LSZ, whose duration is comparable. Despite the strong experience I had with this compound I found it easy to cope, more so than I would expect from LSZ. This makes it a preferable alternative for situations where introspection or spiritual experiences might not be appropriate.

According to Reagent Tests UK 1P-LSD gives a light purple reaction to the ehrlich reagent.

Dosage: 90-190ug orally (swallowed)

Duration: 8-10 hours

Description: A potent psychedelic which is difficult to distinguish from its popular analogue.


Setting – close friend’s house with 3 friends for NYE party. Friends are vaporising DOC and plan to roll later in the evening.
Set – I recently ended a long term relationship and it is playing on my mind
Tolerance to this class of substances: 0/10 I have not tripped in several months.

1740: 166ug briefly chewed and swallowed on an empty stomach.

1800: I feel like something could be happening already
1810: Two housemates who do not use drugs come in before leaving and I’m able to make conversation pretty easily, though there is a lot of paraphernalia on the table and I am pleased to occupy myself with the mixing deck.
1820: The housemates leave and my friends comment that it was awkward as I believed.
1840: while trying to mix tracks I realise I am increasingly high
1850: I worry this might be too much! I take a break from DJing as I am not able to properly operate the system

1918: the level is actually really good as the comeup appears to be smoothing out
1923: Trembling quite a bit from a rocketship comeup. I am struggling to advise my friends on their taking of DOC
1934: Some gas/stomach discomfort – I am a little concerned that I may vomit
1941: I check my phone and put it in flight mode, realising I am way too high to effectively communicate with the outside world, even my closest friends who were not able to attend.
1946: I eat some porridge and a banana which settles my stomach, surprisingly
1950: I lay on the sofa for a bit enjoying my friend’s DJing and the visuals but am aware that this is higher than I wanted to be in this situation

2003: solid +++ now, strong visuals
2015: My friends try to get me to weigh their MDMA replacement for them and advise them on how much to take but my short term memory is terrible and I am really pretty useless, but somehow manage to get sensible doses into them.
2030: I decide the decks are a pleasant and familiar distraction and return to them.
2057: I am tripping very hard now but managing to make acceptable noises from the decks – though mostly just mixing tracks end to end.

2128: My friends’ roll mix is kicking in now but I’m not very good at making conversation

2233: Still a solid +++ and still playing on the decks

2300: certainly less high now than i was earlier

0023: MUCH more competent now, mixing is enjoyable again

0100: The two housemates return and one is a little boisterous. We manage to make conversation and keep them entertained before they retire to bed. I am pleased with my ability to cope but I am still distracting myself with the decks.
0147: Obviously on the way down now

0223: Very uncomfortable gas. very manageable level of tripping though.

0300: I am really hungry so I eat a family bag of crisps, a banana and quite a few peanuts.
0314: 15mg ketamine
0330: My gas has mostly passed, thank goodness

0430: I stop mixing and we put on some mixed sets from youtube
0449: Pretty much down now, I think it is only the ketamine that is noticeable.

0500: 5mg MXE

0620: After a little deliberation I take 0.5mg etizolam and go to bed. I fall asleep very rapidly and wake up at 1300 feeling fairly tired.


Though the dose was too high for me in this setting I would repeat it in a heartbeat if I was alone and am keen to take a smaller dose with friends in the future. I would certainly stagger my doses over 15 minutes next time.
I think this will be a big seller as it has a very pleasant effects profile, is quite gentle and has minimal side effects/physical effects.

I expect this to rapidly gain popularity and be subsequently banned, a great shame considering the likely safety profile of this compared to other novel substances which have emerged in the last 5 years.

Are drug users a dying breed?

NB. I will focus this post on drug use by 16-24 year olds. Drug use among 16-59 year olds is declining but much more slowly.

The UK government released the latest British Crime Survey results for England and Wales today and with it comes a wealth of information about drug use. The data is collected from about 10,000 random participants and includes information about drug use in the last year and across one’s lifetime.

In keeping with the previous ten years there is a continuing downward trend of drug use in the last year which is actually pretty significant. For example, “ecstasy” use by people aged 16-24 has declined 50% in the last ten years, from 6% of the population in 2003 to less than 3% of people having used it in 2013.

Ecstasy use among adults aged 16-24 in the last year

Ecstasy use among adults aged 16-24 in the last year

Given that this is a properly conducted survey it’s hard to argue with a ten year trend, but what is going on here? Can it be that drugs are going out of fashion? Is the drug war working? Are young people more concerned about their health than they used to be?

All entirely possible, but what if the results are actually indicative of a flawed survey? Though technically correct, what if the survey is actually failing to really find out about drug use?

It’s no secret that the governement is woefully unable to respond to changes in the drug market and the BCS is no different. This year’s survey includes two “novel” substances but salvia and nitrous are far from novel. In fact they are two of the oldest legal highs available and measuring their use tells us almost nothing about real NPS use.

So could NPS use be accountable for the steady downward trend? Clearly the reports of ever increasing NPS numbers shows that they are snowballing popularity but the BCS makes no mention of anything other than mephedrone, which was banned in 2010.

To me it still looks like a no for three reasons:

  1. The decline has been steady over the last ten years but the NPS industry has absolutely boomed since 2009. The emergence and subsequent scheduling of mephedrone does not appear to have even made a dent in the stimulant statistics, with amphetamine and cocaine use actually increasing in 2009/10.
  2. Data from the global drug survey suggests that Mephedrone use has been steadily declining since its ban too, though it does appear that availability has dropped.
  3. It’s not just stimulant and cannabinoid use that’s falling – despite a relatively small number of novel opioids on the market heroin use has dropped by a solid 80%, though reported opiate use has admittedly fluctuated seemingly due to methadone use.

This doesn’t excuse the government from making a half-arsed attempt at collecting good data but it is fascinating to see that drug use really does seem to be on a steady downward trend. Perhaps it really is just going out of fashion. There is certainly no obvious nationwide trend I’ve noticed over the entirety of the last 10 years, and with the increasing popularity of festivals I would certainly be expecting the opposite trend. If you have any suggestions at all, please leave a comment.

What will this mean for drug users though? Will enforcement budgets be decreased accordingly? Or will there be a final push to try and eradicate drug use once and for all?


Drug Misuse: Findings from the 2012 to 2013 Crime Survey for England and Wales

Mixmag Global Drug Survey 2010 2011 2012

Lysergic Acid Dimethylazetidide (LSZ)


The lysergamides are perhaps the most famous of the synthetic psychedelic drugs, with LSD being the gold standard of the class. Though potent and legal analogues have been known for decades, the complexity of the synthesis seems to have ensured that only a minuscule number of humans have been able to sample them.

LSZ was originally investigated as a “constrained conformation” analogue of LSD, where the diethylamide moiety has been locked into the active conformation for binding to receptors. In vitro assays indicated it was more potent than LSD itself, one of a tiny fraction of compounds able to make this claim. While this does not appear to hold up in humans, LSZ is still a highly potent psychedelic which is strongly reminiscent of LSD.

Chemical structure of LSZ


Its similar qualities may allow it to be passed off as LSD but it is likely that it has a similar safety profile and the “limited edition” nature of the compound makes it unlikely that most would bother to sell it as anything other than LSZ. It is certainly the rarest compound I’ve had the pleasure of sampling which is great but means that there is barely any existing information about the compound available.

Dosage: 150-300ug orally (swallowed)

Duration: 7-9 hours

Description: A classic psychedelic unsurprisingly reminiscent of its popular analogue.


I was fortunate enough to see the analytical data for the compound and have every confidence that it is indeed LSZ. The blotters were officially laid with the structure on one side and “LSZ” on the other. They were completely tasteless.

The trip was very pleasant without too much in the way of challenging thoughts. It did seem to become a little more introspective towards the latter half but this was not unwelcome. The ease in keeping composure around the public, on the phone and even with people who were somewhat anti-drug is indicative of the relatively low intensity of the experience and as a fairly experienced tripper I would certainly go for 200ug next time, especially with a better setting.

The trip was comparable to 13 mg 2C-E, 700ug 25I NBOMe (nasal), or about 1.3 “hits” of LSD. The subjective effects were certainly most reminiscent of LSD and I’d wholeheartedly recommend LSZ to anyone interested in trying a shorter, more consistently dosed or less legally risky version of LSD. There was some stomach discomfort that I didn’t get on LSD but this would not put me off.

I would say the comeup was approx 45-60 mins to the first real alert, 3h to peak and the total duration perhaps 8h plus afterglow. With a higher dose it may reveal itself to be longer and come up a little faster as there were points at the beginning and end where I could not have said whether the subtle effects were a result of the LSZ or just placebo/afterglow.

Trip Report:

I had been keen to try LSZ for a while so managed to make time for it on a sunny day one weekend. Since there was little information available I was content with a relatively low dose (150ug), as much to understand the drug as to simply enjoy the experience. My girlfriend and I had her flat to ourselves until much later in the day and were mentally as well prepared as we might hope to have been. She took AL-LAD because she did not like the idea of taking such a novel substance.

We dosed late in the morning as I needed to catch a train that evening and within about 45 minutes I felt the first real alerts. After 1h15 I was unmistakeably hit by the experience and a sudden craving for some good music. I was sad to find her subwoofer was still broken and cursed myself for having left all my trip toys at my house but remained quite content to listen to music through the speakers she had. I did not find the music appreciation was as enhanced as with LSD itself but this may have been a function of the low dose.

Around the 2h mark I developed a mild stomach discomfort and ate a sandwich to fill myself and attempt to settle this. Though not really hungry I did enjoy the meal and the discomfort subsided in the following hour while we slowly gathered ourselves to find a nice spot in some fields a short walk away. I spoke to my girlfriend’s sister on the phone as my girlfriend did not want to and managed to to so with no problem at all. She did not suspect I was tripping until I said so towards the end of the conversation. We left the flat and walked down the high street, perfectly able to engage ourselves in normal conversation to keep from laughing.

We arrived at the fields to find they were boarded off to be developed into housing. Somewhat disappointed we walked a short way to an isolated churchyard and settled there. We stayed for about 4 hours chatting, listening to music and generally mucking about and having fun in the bright sun. The visual effects were pretty mild but textures were distorted as ever and it was occasionally possible to see fractal patterns in the grass or the sun coming through the trees.

Approximately 6.5 hours after dosing we returned to the flat where both my girlfriend’s sisters were. They were considerate of our fragile mental state but when their much more anti-drug boyfriends arrived to take them both out to dinner I was able to converse quite easily. After they left (t+7.5h) my girlfriend and I went to a nearby shop and bumped into some friends I’d rather not have. The experience was awkward and quietly played on my mind for the rest of the evening.

After eating the microwave meals we’d bought I felt nothing that couldn’t be put down to afterglow and easily got my train at t+11.5h. I slept fine a few hours later, though having gotten to bed late I was a little tired and irritable the next day.


NENK is a dissociative drug in the arylcyclohexamine class. SAR extrapolation suggests that it should be very similar to ketamine with an extended duration and increased potency as a result of the higher lipophilicity and enzyme resistance caused by the N-ethyl group. Given the two hour duration of ketamine, this modification was welcomed by ketamine users and the release was preceded by much hype.

The structure of NENK


Like the releases of many hyped NPSs though, it was met with much disappointment. Not only were the duration and potency worse than those of ketamine, it caused nosebleeds and had poorly comparable effects to boot. It is thought that retailers were all stocking from the same source laboratory, so initial speculation focused on the possibility of a low quality product, but when independent NMR spectra were released it appeared that it was indeed the real deal, with good apparent purity too, although it is possible that there is a very similar but inactive contaminant or that the NMR spectra are fake.

The nature of the poor reports involved an inherently low intensity, nasal burning, nosebleeds and a general lack of “warmth” experienced with ketamine. As a result of this I had not intended to try NENK, but after I performed an acetone wash on some for a colleague, he offered that I try it and I felt it might be worth seeing if the wash had made any difference.

The logic behind the acetone wash was that the synthesis might have produced an analogous impurity to the one which the DEA established could be produced in the synthesis of methoxetamine, but it is a good technique generally for possibly impure substances.

Dose (acetone washed): 45 mg

Duration: 1 Hour, Insufflated

Description: An impotent and generally unimpressive dissociative which is frankly not worth bothering with.

My Experience

The acetone wash was qualitative, with ~ 200 – 400 mg NENK placed in ~ 5 mls of acetone and heated. The acetone was discarded and the remaining 160mg of solid collected and dried. Solubility in the acetone did not seem good.

I initially insufflated approximately 15 mg up one nostril to gauge the intensity of the nasal discomfort and confirmed that even at this level, it was quite unpleasant. Within five minutes I suspected I could feel something and within ten minutes there was a distinct dissociative not. I decided to go for the whole experience so I insufflated some water as recommended by a bluelight.ru member and then insufflated 26 mg of NENK between both nostrils. Again, the burn was unpleasant and significantly worse than other drugs in the class.

The dissociation I felt following this was not quite in line with the extra 170% dose but it was fairly pleasant nonetheless, perhaps comparable in intensity to about 15 mg of MXE. I have no low dose experience with ketamine to compare but it was significantly less intense than my lowest dose of 60 mg. I remained very functional the entire time and I would not have necessarily known it would lead to dissociation if I had never tried a dissociative before.

The effects began to wane after about 30 minutes and gave way to a “dissociative fuzz” about an hour later. I have experienced this before the day after large doses of other dissociatives but I would not have expected it from such a low-intensity experience. This remained until I slept 4 hours later, fading perhaps only by half. My nose was distinctly blocked and sniffly for the rest of the evening.

The next morning I awoke to find a considerable amount of dried blood in my nose, and again the next day. I used 2-FMA on this second day and went cycling at t+8 hours. About 20 minutes in I developed a pretty severe nosebleed which forced me to stop and then slowly cycle home. What’s interesting about this is that it was almost entirely in the nostril which I took the first line through, when it had not been moistened. Regardless of moisture there was also twice as much taken in this nostril. It is therefore possible that the damage is partly mechanical, although I am very skeptical of this. given the ease of moistening one’s nose before use I would say this is an essential practice.

I would absolutely not use NENK again, the mild effects and pathetic duration are not even slightly worth the nasal damage. It also appears to be more expensive than ketamine, giving it no recreational potential and frankly, almost none for a research chemical enthusiast either.



2,5-Dimethoxy-4-chloroamphetamine (DOC) is long-lived, potent psychedelic which was discovered by Alexander Shulgin in the late 20th century. It has enjoyed a constant but low level of popularity although its high potency (3 mg dose) has meant it can generally only be handled in blotter form and as a result is sometimes dangerously misrepresented as LSD. As a psychedelic amphetamine it is regarded to be a stimulating psychedelic and is alleged to have an easygoing headspace and moderate visuals.

DOC structure


Although it has been around for a long time, there are few reports of any other ROA than oral, which surprised me given the marathon duration. I suspected that a shorter ROA would make the comeup shorter than the normal 2 hours and might make the total duration more manageable too. There were absolutely no reports of this but considering that vaporising the 2C-x series is very effective, I saw no reason it would not work for the closely related DOx series.

Dose: 1-5mg oral, 0.8-2.4 mg vaporised

Duration: 12-24 hours oral, 10-14 hours vaporised.

Description: A potent stimulating psychedelic with a very long comeup and long overall duration.


I spent the trip split between cycling and relaxing at home. I had plenty of energy for cycling and good focus without distractions, but never felt pushily energetic while relaxing. Music was certainly enhanced and the synaesthetic CEVs that came with it were wonderful. The trip was not very visual and very easy to handle so I suspect the dose could easily be pushed a little, although it certainly broke a mild +++ at the peak. I can see why it is popular as a party drug and if the duration was shorter I think it would enjoy much more popularity.

Vaporising provided a near-instant comeup, bypassed the stomach, gave excellent intensity control and did not burn. If the dose was well measured I would have every confidence vaporising over 20 minutes max ang gauging the intensity as I vaped to find a comfortable level, with the measured dosage providing a safety net. Unlike with vaporised 2C-xs the plateau was very nice and long which did not leave me with a desire to repeatedly redose. 2C-B has a 20 minute plateau vaped which makes it of little enjoyment as an ROA.


I weighed out 1.2 mg of  DOC and placed it into my bulb vape, heating using a small candle. It quickly melted and began to vaporise without burning. The vapour was easy to inhale, even in “large” hits and the first alerts were present within a couple of minutes. I take a couple of good hits and the second comes with a psychedelic “rush” which takes me off-guard. I instantly wonder if I have overdone it and the nausea which I was suffering before plays on my mind.

I lie down and as the nausea subsides I notice I have slight tracers and music sounds good. I am trembling a little which does not surprise me. After a shower the physical sensations subside a little and I feel comfortable that I am not far above a ++ and would like some more. I finish the contents of the vape without any rushes this time. There is some jaw clenching and the visuals are a bit more distinct. Although the nausea does not return I feel physically uncomfortable again and lie down.

As I do so and close my eyes I begin to have synaesthetic visuals which flow perfectly with the music. They are beautiful but sadly not that intense. The visuals throughout the trip are pretty mild but can be brought out with focus. The time dilation is very significant but I am quite able to deal with it.

After about 45 minutes the uncomfortable sensations are gone and although not hungry I eat a banana. I then decide I’d like to go for a cycle so after a little deliberation about having to encounter other people I kit up and go. As I come to cross the main road I wait for what feels like quite a while. I notice the cars have minor tracers, making them appear like tron light-cycles and chuckle to myself. I feel quite able to cycle as soon as I get going and thoroughly enjoy meandering around a mix of mildly busy roads and totally empty country ones. When I stop of my own accord in country roads I feel incredibly peaceful but I really dislike stopping at traffic lights.

A friend comes round and we play call of duty for a while. I’m not as good as normal but still put up a good fight. After he leaves I have a balloon of nirtous. It is enjoyable as ever but I do not remember much of it and it just leaves me wanting more as always. I force a toasted sandwich which is actually pretty nice and I eat the other half about half an hour later. I appear to have come down considerably as I feel like I could much better handle speaking to others now.

I do another balloon and find the same results as before. I decide they would be better sipped slowly and find I am right as the balloon brings back a bit of intensity without being very shortlived.

I spend the rest of the evening chatting online and browsing the internet. 12 hours after the second dose I can still feel something but it’s not clear what. I certainly feel like I have come down almost completely. This feeling persists for 3 hours until I decide I have to try to sleep. I lie in bed and find myself falling asleep very quickly, even though there is music on and I have no sleep aids. I switch the music off and fall asleep near instantly. I awake the next morning after 9 hours and feel absolutely fine.

Overall a lovely experience which could have been easily enjoyed at a higher intensity. I felt about the same from t+12h onwards so probably could have slept from then. I never felt excessively stimulated but I imagine my body was well exercised from a 20 km cycle.



Desoxypipradrol (2-DPMP) is long-lived, potent stimulant which was released in the wake of the UK cathinone ban as a possible substitute for the banned substances. It quickly grew a fearsome reputation as an incredibly long lived stimulant with little to no euphoria and not much recreational potential at all. It also emerged as the ingredient in “Ivory Wave” which caused a number of psychotic hospitalisations, presumably as a result of people chasing the euphoria.


Unsurprisingly it quickly fell to the sidelines, although it was not forgotten, with the UK government banning import in December 2011. It was finally scheduled as a class B drug in May 2012.

The effects are very subtle at any dose worth trying, and useful but horribly drawn out at doses above this. In my opinion it has no recreational value. Interestingly for a DRI I did not notice a comedown.

Dose: 4mg orally

Duration: 16-72 hours

Description: A potent functional stimulant with a gruelling duration and long come-up.

My Experiences

Due to the low dose I made up a volumetric solution into 5 mg blotters and ate one. I experienced nothing the entire day and slept fine.

The next day I figured that I would still have some of yesterday’s dose and if I had the same again they would stack to a threshold dose. I dosed early again and felt nothing until about 10pm. I noticed I had some jaw tension which built over the following hours. I was not tired and did not bother trying to sleep for 2 hours past my normal time. I tried in vain until about 4am, when I dosed enough GBL to knock myself out until 8am. That day my focus was excellent, but my heart rate was up 20 BPM and I could feel it beating when I was sat quietly.

I was quite tired the next night, but still needed GBL to get any sleep. This portion was slightly fun, but that was no fault of the DPMP.

My heart rate was still high on this, the fourth day after dose 1, but my focus was normal. By the time night came I was able to sleep naturally and my BPM was normal again.

I tried 2-DPMP a few more times, but never once found it to be useful without also disrupting my sleep. Even when vaporised it cause problems. I do not think I would bother with it again. The come-up and duration are too long and it is too unpredictable.



Mebroqualone (MBQ) is another attempt to capture the popularity of methaqualone with an unscheduled analogue. It seems very rare, with no available reports but some mention of prior appearances on the grey market. As with its relatives, it is likely that MBQ is a GABA agonist and appears to be fairly potent, similar to methylmethaqualone (MMQ). This is strange given the “normal” potency of mecloqualone in the 100mg range.

Mebroqualone structure


The effects seem similar to those that methaqualone is reputed for, a pleasant disorientation and depressant effect, going a little further than the simple anxiolytic and sedative effects of benzodiazepines. This makes it a little more fun, and coupled with the short duration this could make it quite suitable for a party setting if it is similarly active orally.

Dose: 15-20mg sublingually

Duration: 60 minutes

Description: A potent yet short-lived quaalude. The depressant effects are quite pleasant, making the short duration a shame.

My Experiences

Being initially quite unsure of the dosage, I worked up very slowly with this. It emerged that it was active in the same range as MMQ, but perhaps with a slightly shorter duration. Given that MMQ doesn’t last very long as is, this is far from ideal but it seems to be quite pleasant anyway.

It is a fine white powder which is highly insoluble in water and 50:50 isopropanol water. Like MMQ it is not bitter at all, and seems to be less sour too. By comparison, etaqualone is slightly bitter, but still nothing compared to phenethylamines, for example.

When vaporised I found there was a faint taste of chlorine. I’m not exactly sure what caused this but it is not something I noticed before, but it put me off instantly.

The threshold effects are very minor at about 5mg, but are noticeable. Sublingual should not be ideal with this, as the solubility is low, but it does seem to work. Holding 10mg for as long as possible, I noticed effects within a few minutes, a pleasant disorientation. After 15 minutes effects did not seem to be intensifying, remaining at a subtle but pleasant level. After 45 minutes the effects were clearly waning and I went for another 15mg sublingually. Again, the effects came on again quickly and began to fade after 25 minutes.

At this point I climbed into bed and quickly fell into a pleasant sleep.

Overall a lovely compound, but realistically too short-lived to gain much popularity.


3-MeO-PCP is a dissociative drug in the arylcyclohexamine class. As the name suggests, it is related to PCP by the addition of a methoxy group. It is of similar potency, with doses in the 10mg region, but is more dissociative with less activity as a DRI. With a little luck, this will lead to less stimulation and mania, and therefore less  of the crazy feats the PCP is infamous for.

The structure of 3-MeO-PCP


The first mentions of 3-MeO-PCP seem to have come around mid 2009 with a few reports scattered around. Interest seemed to be piqued again as MXE gained popularity, but its rise has been stunted deliberately by responsible vendors ensuring it is not easily accessed. Given the accidents we are already seeing with other popular, potent drugs, this seems sensible.

It is supposed to be approximately 5x more potent than MXE. I think this is a good assessment, although higher doses are less impairing which can make it seem more like 3x potency. As someone who finds 30mg of MXE pretty ideal, I would say I most enjoy about 6mg of 3-MeO-PCP.

Dose: 8-10mg

Duration: 7-8 Hours, Oral

Description: A potent yet remarkably lucid and functional dissociative, similar in feeling to methoxetamine. A little less mad and barely sleep-depriving compared to MXE’s slight ability to ward off sleep.

My Experiences

I quite enjoy potent drugs as there is less material to taste and they tend to be overlooked somewhat by those who don’t have the correct equipment to deal with them. I also quite enjoy methoxetamine, and given that this was described as a clearer, more recreational version of this I was excited to try it.

Upsettingly, there was little information available about the exact durations and doses , even by comparison to other drugs. I saw one comment suggesting that potency was about 5 x that of methoxetamine, but had also seen many reports suggesting that it was actually lower than this.  Ignoring the comparison to MXE I decided to go for 3mg as a starter.

I knew this would be a very low dose, even sublingually. I dissolved it and quickly noticed a pleasant numbness, considerably stronger that that of MXE. The effects appeared slowly and reached a ceiling pretty quickly. there was a minor dissociative headspace but little more to speak of. Comfortable that I knew where the bar was set, I decided to try 10mg in the next trial.

I held the 10mg under my tongue for just under hour, with the numbness similar to pins and needles where the solution sat. This faded by about the 45 minute mark.

The effects came on quite quickly, with a pleasant headspace and mood lift being noticeable fairly quickly. As the intensity rose I found myself really enjoying music. It seemed less distorted than with MXE, although when it was off I noticed my hearing seemed muffled slightly, to a similar extent of that caused by MXE.

I found the effects to continue building well after I swallowed the sublingual solution, suggesting it is poorly absorbed in this way. After swallowing the plateau appeared to come after approximately one hour. It lasted for a solid 2 hours, until I ate dinner, at which point I felt the effects began to wane very smoothly and gradually. At t+6h there were still unmistakeable effects, but they were much reduced, to a point where I felt capable as if I were sober. I was tired, and upon going to bed I found that I had no problem getting to sleep.

The whole experience seemed to be very clear and lucid. Although I felt fairly dissociated, I was easily able to snap in and out while typing, and the amnesic and visual fog which I get on others did not seem to be so present. There were also many of the introspective thoughts about my life, society and the future which I associate with MXE. I have always found these thoughts to be akin to the stereotypical ones expected but not obtained from classical psychedelics.

The similarities to ketamine are few and far between, with much less cognitive inhibition, sedation and ataxia by comparison.

Overall, very enjoyable, and certainly one I will repeat. I do not think its effects are worthy of a 10x price increase over MXE though.