Category Archives: morpholines

3-Fluorophenmetrazine (3-FPM)

Introduction:

3-Fluorophenmetrazine is a novel stimulant based on phenmetrazine. It has been sold publicly since October 2014.

3-Fluorophenmetrazine (3-FPM)

Structure of 3-FPM.

 

Despite being a popular abusable prescription drug until the mid 1970s phenmetrazine (referred to as PM herein) has never been sold publicly on modern black markets and as a result no reports have ever been submitted to Erowid. Perhaps more surprising given the fast-moving nature of the novel substance market is that no other analogues of phenmetrazine have been seen and 3-FPM was not publicly sold until October 2014.

From what information can be gathered about the parent compound it appears that the addition of fluorine has minimally changed the original compound. 3-FPM appears to be a similarly functional stimulant with a similar dosage range.

The duration does appear to be increased slightly and there is suggestion that protracted (“binge”) dosing can keep sleep at bay for considerably longer than would otherwise be expected. This is not surprising given that a possible metabolite would be 3F-ephedrine and the resistance to metabolism conferred by fluorine would cause both this and 3-FPM to hang around longer. In addition to this, and not unusually for a functional stimulant, there appears to be a “ceiling effect” whereby after a certain level the desirable effects are not significantly increased by taking more, but the desire to redose and negative side effects are strengthened.

Given that phenmetrazine is a releasing agent and 3-FPM is so closely related it is very reasonable to assume that its action is exerted as a dopamine/norepinephrine releasing agent (NDRA).

Of course, the modification to the structure does allow 3-FPM to evade legislation and it is currently not specifically scheduled in most countries, meaning it is essentially legal to possess in many jurisdictions.

From a single low dose the headspace is quite clear with little feeling of being “high”, though the physical side effects are easily noticeable at medium doses and above.

Dose: 30-60 mg (oral) (insufflation is extremely painful)

Duration: 5-7 Hours (oral, single dose)

Report:

14:16 – 36mg orally
14:39 – I do feel slightly sped up.
15:10 – pretty mild though
15:19 – certainly a pleasant mood lift
16:21 – A subtle but pleasant headspace change exists. Equivalent to perhaps 20mg of 2-FMA
16:45 – Managing a website, I am easily staying focused. Sweating a bit more than normal
17:33 – losing focus more easily now
19:09 – I go to the pub and am marginally more chatty
21:19 – I eat a well sized meal, my appetite doesn’t seem diminished.

Several months later:

15:43 – 36.0 mg oral, light stomach contents
16:37 – Slightly sped up, nothing serious. Nice headspace and slight moodlift. Slight increase in sweating.
17:06 – Feeling reasonably chatty, slightly uplifted
18:13 – The effects are still very mild and not very noticeable but the lethargy I did have is totally gone and I have been productively editing, organising and doing chores. I didn’t get much increased sweatiness this time but have been drinking and urinating more.
19:00 – Still a pleasant noticeable buzz
20:30 – I eat dinner without much issue
22:34 – Not feeling anything now

Conclusion: A fairly average stimulant without many notable features. The unwelcome sleeplessness and diminishing returns at high doses have (happily) limited the popularity of 3-FPM somewhat but it is a viable stimulant for use as a study aid or general productivity enhancer in low doses.